The Autorefresh function is not working in the 64bit version of the program (Notepad++ v7.8).
Tried with and without using %APPDATA% folder, still no change.
Tried with every version of IE, still nothing.
Installing 32bit version with keeping my configurations it is working at once.

Windows 10 Business 1903 64bit

Let me know if you need any more information.

Hm... It works fine on my machine with Notepad++ v7.6 (64-bits).

I will install v7.8 to see if that makes any difference here.